通用名称:阿替洛尔(氨酰心安) 英文名称:Atenolol(Tenormine) 中文别名:阿坦乐尔、氨酰心安、氨酰心胺、苯氧胺、速降血压灵 英文别名:Alinor、Target 作用与用途:本品为心脏选择性β-受体阻断剂,无膜稳定作用,无内源性拟交感活性。一般用于窦性心动过速及早搏等,也可用于高血压,心绞痛及青光眼。 Atenolol is a selective β1 receptor antagonist, a drug belonging to the group of beta blockers (sometimes written β-blockers), a class of drugs used primarily in cardiovascular diseases. Introduced in 1976, atenolol was developed as a replacement for propranolol in the treatment of hypertension. The chemical works by slowing down the heart and reducing its workload. Unlike propranolol, atenolol does not pass through the blood–brain barrier thus avoiding various central nervous system side effects. Atenolol is one of the most widely used β-blockers in the United Kingdom and was once the first-line treatment for hypertension. The role for β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line, as they perform less appropriately or effectively than newer drugs, particularly in the elderly. Some evidence suggests that even in normal doses the most frequently used β-blockers carry an unacceptable risk of provoking type 2 diabetes. Formula C14H22N2O3