拉莫三嗪（lamotrigine；LTG）。葛兰素史克注册为Lamictal，在南非称作Lamictin、以色列叫做Lamogine、在台湾称作乐命达、在韩国则称라믹탈。是一种苯三嗪类的广谱抗癫痫药，用于治疗癫痫局限性发作的辅助药物。美国FDA在1998年批准。其半衰期较长（24～30 h），每天可以给药两次。拉莫三嗪的详细作用机制尚未明了，可能是阻断钠离子通道。 化学式 C9H7Cl2N5 Lamotrigine, marketed in the US and most of Europe as Lamictal by GlaxoSmithKline, is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used as an adjunct in treating depression, though this is considered off-label usage.[citation needed] For epilepsy, it is used to treat focal seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Like many other anticonvulsant medications, Lamotrigine also seems to act as an effective mood stabilizer, and has been the first U.S. Food and Drug Administration (FDA)-approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type I. Formula C9H7Cl2N5
