羟丙基-β-环糊精
中文同义词: 羟丙基-β-环糊精;羟丙基环糊精;(2-羟丙基)-B-环糊精;2-羟丙基-B-环糊精,平均MW CA 1380;2-羟丙基-B-环糊精,平均MW CA 1400;2-羟丙基-Β-环煳精, MW CA 1250-1480;羟丙基环胡精;(2-羟丙基)-BETA-环糊精;2-羟丙基-Β-环糊精, MW CA 1250-1480
特点及用途:羟丙基的引入打破了β-环糊精的分子内环状氢键,在保持环糊精空腔的同时克服了β-环糊精水溶性差的主要缺点。是目前研究最为深入,应用最广泛的环糊精衍生物之一。主要应用于食品、医药、化妆品行业。
1、在食品、香料领域,可提高营养分子的稳定性和长效性,可掩盖或矫正食品营养分子的不良气味和口味,可改进生产工艺和产品品质。该产品在水中的溶解度很好,取代度4及以上可以和水任意比例混溶,在50%的乙醇和甲醇中也能溶解。
2、在化妆品原料中用作稳定剂、乳化剂、去味剂等,可降低化妆品中有机分子对皮肤粘膜组织的刺激,增强有效成分的稳定性,防止营养成分的挥发、氧化。它有一定的相对吸湿性。
3、在医药工业中,由于相对表面活性和溶血活性比较低且对肌肉没有刺激性,所以它是一种理想的注射剂增溶剂和药物赋形剂。可以提高难溶性药物的水溶性,增加药物稳定性、提高药物生物利用度,使药剂的疗效增加或服用量减少,可以调整或控制药物的释放速度,降低药物毒副作用。可用于口服药物、注射剂、粘膜给药系统(包括鼻粘膜、直肠、角膜等)、透皮吸收给药系统、亲脂性靶向药物的载体,还可用做蛋白质的保护剂和稳定剂。
本公司还推出:一氯三嗪-β-环糊精,α-环糊精,羟丙基-β-环糊精,碘代-γ-环糊精,磺丁基-β-环糊精,磺丁基-β-环糊精,吡罗昔康-β-环糊精,对甲苯磺酰化-β-环糊精,磺酸酯基-β-环糊精,6-巯基-6-去氧-β-环糊精,6-氨基-6-去氧-β-环糊精,己二胺基-β-环糊精,2-羟丙基-β-环糊精,羟乙基-β-环糊精
Hydroxypropyl-beta-cyclodextrin
Product Name: Hydroxypropyl-beta-cyclodextrin
Synonyms: (2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN;beta-cyclodextrin,2-hydroxypropylether;beta-hydroxypropylcyclodextrin;(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN;(2-Hydroxypropyl)-β-cyclodextrin;2-Hydroxypropyl-B-Cyclodextrin ;2-HYDROXYPROPYL-B-CYCLODEXTRIN CELLCULTU RE TESTED;HYDROXYPROPYL-BETA-CYCLODEXTRIN (MS = 0. 8);(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN (MS=1.0)
CAS: 128446-35-5
MF: C63H112O42
MW: 1541.54
EINECS: 420-920-1
Assay: 99%
Appearance: White powder
Property: Introducing hydroxypropyl broke the intramolecular hydrogen bond with β - cyclodextrin, while maintaining the cyclodextrin cavity at the same time to overcome the main disadvantages of β - cyclodextrin with poor solubility in water. Is the best studied, one of the most widely used cyclodextrin derivatives. Mainly used in food, medicine, cosmetics industry.
Usage:
1, in the field of food, spices, can improve the stability of trophic molecules and long-term, bad smell and taste can cover up or correction of food nutrition molecules, to improve the production process and product quality. This product is very good in water solubility, degree of substitution of 4 and above can be arbitrary proportion and water miscible, can also be dissolved in 50% ethanol and methanol.
2, in the cosmetics raw materials used as stabilizers, emulsifiers, deodorizing agent, can reduce the stimulation of organic molecules in cosmetics to skin and mucous membrane organization, enhance the stability of active ingredients, to prevent the volatilization, oxidation of nutrients. It has relatively certain hygroscopic.
3, in the pharmaceutical industry, due to the relative surface activity and hemolytic activity is relatively low and no stimulation to muscle, so it is a kind of ideal injection solubilizing agent and pharmaceutical excipient. Can increase the dissolution rate of water-soluble, increase the bioavailability of drugs, drug stability, increase the efficacy of the drug or dose reduction, can adjust or control the drug release rate, reduce side effects of drugs. Can be used in oral medicine, injection, mucosal drug delivery system (including the nasal, rectal, cornea and so on), transdermal drug delivery system, lipophilic drug targeting carrier, agent and stabilizer protection can also be used as a protein.
Packing: 10kg/drum
Price: USD 25/kg
The company also introduced: a chlorine three triazine - β - cyclodextrins, cyclodextrin, hydroxypropyl - β - cyclodextrin, iodo - γ - cyclodextrin, sulfobutyl - beta - cyclodextrin, sulfobutyl - beta - cyclodextrin, piroxicam beta cyclodextrin, tosyl acylated beta cyclodextrin, sulfonic acid ester - β - cyclodextrin, 6- mercapto -6- deoxy β - cyclodextrin, 6- amino -6- deoxy β - cyclodextrin, with β cyclodextrin, 2- hydroxypropyl - β - cyclodextrin, hydroxyethyl - β - cyclodextrin
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