熊去氧胆酸
中文同义词: 3alpha,7beta-二羟基-5beta-胆甾烷-24-酸;熊去氧胆酸;熊脱氧胆酸;熊果去氧胆酸;乌索去氧胆酸;乌索脱氧胆酸;熊果去氧胆酸/熊去氧胆酸;熊去氧胆酸,99%
化学性质 本品为白色粉末；无臭，味苦。Mp 200-204℃。在乙醇和冰醋酸中易溶，在氢氧化钠试液中溶解，在氯仿中不溶。UDCA为CDCA的同分异构体，其溶石作用强于CDCA，无腹泻及肝脏毒性。
适应症
胆固醇性胆结石。原发性胆汁淤积性肝硬变，原发性硬化性胆管炎。胆汁返流性胃炎。该品用于胆固醇型胆结石，形成及胆汁缺乏性脂肪泻，也可用于预防药物性结石 形成及治疗脂肪痢（回肠切除术后）
【临床应用】
1.主要用于不宜手术治疗的胆固醇型胆结石：适用于胆囊功能正常、透光、直径10-15mm的非钙化结石。
2.预防胆结石形成：用于需长期服用易形成胆固醇结石的药物(如雌激素、氯贝丁酯及其衍生物、考来烯胺)的患者、长期进食高胆固醇饮食者或有易感遗传因素者，以预防胆结石形成。
3.治疗胆囊炎、胆管炎、胆汁性消化不良、黄疸等。
4.回肠切除术后脂肪泻、高三酰甘油血症、肝肿大、慢性肝炎等，亦可用于胆汁反流性胃炎。
5.还用于原发性胆汁性肝硬化和原发性硬化性胆管炎(国外资料)。

Ursodeoxycholic acid
Synonym: 7BETA-HYDROXYLITHOCHOLIC ACID;6BETA-CHOLANIC ACID-3A,7BETA-DIOL;(6-BETA)-CHOLANIC ACID-(3-ALPHA)-(7-BETA)-DIOL;3A,7B-DIHYDROXY-5B-CHOLAN-24-OIC ACID;3ALPHA, 7BETA-DIHYDROXY-5BETA-CHOLANIC ACID;3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID;3alpha,7beta-dihydroxy-6beta-cholan-24-oic acid;3ALPHA, 7BETA-DIOXYCHOLANIC ACID
CAS: 128-13-2
MF: C24H40O4
MW: 392.57
EINECS: 204-879-3
Assay: 99%
Appearance: White Powder
Chemical Property: Odorless, bitter taste. Mp 200-204 Centigrade. Soluble in ethanol and acetic acid, dissolved in sodium hydroxide solution, insoluble in chloroform. UDCA isomers of CDCA, the litholytic effect is stronger than CDCA, no diarrhea and liver toxicity.
Indication:
Cholesterol gallstone. Primary biliary cirrhosis, primary sclerosing cholangitis. Bile reflux gastritis. The product is used for cholesterol gallstones, bile formation and lack of steatorrhea, can also be used for the prevention of drug treatment of stone formation and steatorrhea (ileal resection)
Clinical Application:
1. Mainly used for cholesterol gallstones should not operation therapy: Stone non calcified suitable for gallbladder function is normal, light, the diameter of 10-15mm.
2. The prevention of gallstone formation: a drug used to need to take a long time to the formation of cholesterol gallstones (such as estrogen, clofibrate and its derivatives, cholestyramine) in patients with long-term consumption of high cholesterol diet, or susceptible to genetic factors, in order to prevent gallstone formation.
3. Treatment of cholecystitis, cholangitis, biliary dyspepsia, jaundice.
4. Ileal resection steatorrhea, hypertriglyceridemia, hepatomegaly, chronic hepatitis, can also be used for bile reflux gastritis.
5. Also used for primary biliary cirrhosis and primary sclerosing cholangitis.
Package: 25kg/drum
Price: USD 348/kg

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