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甲磺酸酚妥拉明

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 甲磺酸酚妥拉明
中文别名: 酚妥拉明; 瑞支亭; 2-[N-(间羟基)-对甲苯胺甲基]-2-咪唑啉甲磺酸盐; 甲烷磺酸芬妥胺; 立其丁
性质: 白色的结晶性粉末;无臭,味苦。本品在水或乙醇中易溶,在氯仿中微溶。熔点 本品的熔点(附录Ⅵ C)为176 ~181 ℃,熔融时同时分解。
应用:
1. 本品为α-受体阻断药,通过阻断α-受体和间接激动β-受体,迅速使周围血管扩张,可显著降低外周血管阻力,增加周围血容量,改善微循环。
2. 本品对心脏有兴奋作用,使心肌收缩力增加、心率加快、心输出量增加。
临床主要用于治疗肺充血或肺水肿的急性心力衰竭、血管痉挛性疾病、手足发绀症、感性中毒性休克及嗜铬细胞瘤的诊断试验等。亦用于室性早搏。


Phentolamine Mesylate

Synonym: VASOMAX; m-(n-(2-imidazolin-2-ylmethyl)-p-toluidino)-;methanesulfonate (1:1)
CAS: 65-28-1
MF: C18H23N3O4S
MW: 377.4579
EINECS: 200-604-6
Assay: 99%
Appearance: White Crystal Powder
Specification: CP
Property: Odorless, bitter taste. This product in water or ethanol soluble, slightly soluble in chloroform. The melting point of the product melting point (Appendix VI C) was 176 ~ 181 ℃, melting and decomposition.
Usage:
1. this product is alpha blocker, by blocking the receptor and the indirect activation of β - receptor, quickly make the expansion of peripheral blood vessels, can significantly reduce the peripheral vascular resistance, increased peripheral blood volume, improve microcirculation.
2. this product have excitatory effects on the heart, so that increases in myocardial contractility, heart rate, increased cardiac output.
The main clinical treatment for acute heart failure, pulmonary congestion or edema of vascular spasm, acrocyanosis, perceptual toxic shock and the diagnosis of pheochromocytoma test etc.. Also used for premature ventricular contractions.
Package: 25kg/drum
Price: USD 630/kg

 

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