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武汉远成共创科技有限公司
格列苯脲

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 格列苯脲
中文同义词: N-[2-[4-[[[(环己氨基)羰基]氨基]磺酰基]苯基]乙基]-2-甲氧基-5-氯苯甲酰胺;格列本脲;5-氯-N-[2-[4-[[[(环己基氨基)羰基]氨基]磺酰基]苯基]乙基]-2-甲氧基苯甲酰胺;优降糖;格列苯脲;格列呠咪;格列赫素;优降糖,99%
化学性质 白色结晶性粉末。熔点168-173℃。不溶于水,微溶于乙醇、丙酮、氯仿。
用途 降血糖药,作用比甲苯磺丁脲强。
用途 降血糖药,用于中、轻度非胰岛素依赖型糖尿病的治疗
降糖药 格列本脲又叫优降糖、达安疗,属于第二代口服磺脲类降糖药,作用机理同甲苯磺丁脲,其降血糖作用为磺酰脲类中最强,作用强度为甲苯磺丁脲的200~250倍。可选择性作用于胰腺β细胞、促进胰岛素的分泌,可增强外源性胰岛素的降血糖作用,加强胰岛素的受体后作用。
降血糖作用 格列本脲是目前治疗2型糖尿病最常应用的药物之一,因本品作用快而强,所以应用后效果较明显,能很好地控制血糖,适用于血糖较高、用其他磺酰脲类降血糖药效果不佳者。
注意事项 应从小剂量开始使用格列本脲。用药期间应定期检查尿糖、尿酮体、尿蛋白和血糖、血常规、肝肾功能、视力、眼底视网膜血管。

Glibenclamide
Synonym: LABOTEST-BB LT00244861;GLYBENCLAMIDE;GLYBENZCYCLAMIDE;GLYBURIDE;GIBENCLAMIDE;GLIBENCLAMIDE;5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE;5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE, 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide
CAS: 10238-21-8
MF: C23H28ClN3O5S
MW: 494
EINECS: 233-570-6
Assay: 98%
Appearance: White Crystal Powder
Specification: CP
Chemical Property: Melting point 168-173 Centigrade. Insoluble in water, slightly soluble in ethanol, acetone, chloroform.
Usage:
1. Hypoglycemic drugs, for the treatment of mild, non insulin dependent diabetes mellitus
2. Glibenclamide and glibenclamide, glibenclamide, which belongs to the second generation oral sulfonylurea drugs, with the mechanism of toluene sulfonyl Ding Niao, its hypoglycemic effect was the strongest sulfonylurea, intensity for tolbutamide 200 ~ 250 times. Be selective effect on pancreatic beta cells, promote the secretion of insulin, can enhance the hypoglycemic effect of exogenous insulin, insulin receptor after strengthening effect.
3. Glibenclamide is one of the drugs currently used to treat type 2 diabetes, the most often used, because the utility function is fast and strong, so after the application has obvious effect, can effectively control blood sugar, high blood sugar, is applicable to other sulfonylurea hypoglycemic effect not beautiful person.
Package: 25kg/drum
Price: USD 92/kg

 

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