伏立康唑
中文同义词: (2R,3S)-2-(2,4-二氟苯基)-3-(5-氟嘧啶-4-基)-1-(1H-1,2,4-三唑-1-基)-2-丁醇;伏立康唑;(2R,3S)-2-(2,4-二氟苯基)-3-(5-氟嘧啶-4-基)-1-(1H-1,2,4-三唑 -1-基)-2-丁醇;伏立康唑/(2R,3S)-2-(2,4-二氟苯基)-3-(5-氟嘧啶-4-基)-1-(1H-1,2,4-三唑 -1-基)-2-丁醇;伏立康唑 威凡
产品描述 伏立康唑是一种广谱类三唑类抗真菌药,主要用于治疗免疫缺陷患者中进行性的、可能威胁生命的感染。适应症包括：免疫抑制患者的严重真菌感染，急性侵袭性曲霉病（最常见致病菌为烟曲霉，其次为黄曲霉、黑曲霉和土曲霉），对氟康唑耐药的念珠菌引起的严重侵袭性感染（包括克柔念珠菌），由足放线病菌属和镰刀菌属引起的严重感染。中度至重度肾功能不全患者,慎重经静脉给药。
药理相互作用 与CYP3A4底物，特非那定，西罗莫司，阿司咪唑，西沙必利，匹莫齐特或奎尼丁合用，可使上述药物的血药浓度增高，从而导致Q-T间期延长，并且偶见尖端扭转型室性心动过速。
与利福平，利福布丁，依非韦伦，利托那韦(每次400mg，每12小时一次)，卡马西平和苯巴比妥合用，可以显著降低伏立康唑的血浓度。
与麦角生物碱类药物(麦角胺，二氢麦角胺)合用后麦角类药物的血药浓度增高可导致麦角中毒。
用途 抗真菌药物
用途 广谱抗真菌

Voriconazole
Synonym: 2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1h-1,2,4-triazol-1-yl)butan-2-ol;VORICONAZOLE;(2R,3S/2S,3R)-3-(5-FLUORO-4-PYRIMIDINYL)-2-(2,4-DIFLUOROPHENYL)-1-(1H-1,2,4-TRIA;(aR,bS)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol;UK-10949;Vorionazole;(2R,3S)-2-(2,4-DIFLUOROPHENYL)-3-(5-FLUOROPYRIMIDIN-4-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL;(aR,S)-a-(2,4-Difluorophenyl)-5-fluoro--methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
CAS: 137234-62-9
MF: C16H14F3N5O
MW: 349.31
Assay: 99%
Appearance: White crystal Powder
Specification: CP
Property: Antifungal drugs, Broad spectrum antifungal
Usage: Voriconazole is a broad class of three azole antifungal agent, mainly used for potentially life-threatening infection in immunocompromised patients, treatment of. Indications include: immunosuppressive severe fungal infection patients, acute invasive aspergillosis (the most common pathogenic bacteria and Aspergillus fumigatus, followed by Aspergillus flavus, Aspergillus niger and Aspergillus terreus), severe invasive infection of Candida albicans resistant to fluconazole induced (including Candida krusei), serious infections caused by foot and Fusarium genera actinomycete bacteria. Moderate to severe renal insufficiency patients, careful after intravenous administration.
Package: 1kg/foil bag
Price: USD 3960/kg

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