丙酸氯倍他索
类 别:皮肤科用药-糖皮质激素
其他名称:氯倍氟美松丙醋酸,氯培他索,特美肤,蒽肤,丙酸倍氯松,丙酸氯倍他索,二丙酸氯倍他米松,特美肤 ,丙酸氯倍米松
药理毒理:本品作用迅速,是目前临床应用的高效外用皮质类固醇中药效较强的一种。具有较强的毛细血管收缩作用,其抗炎作用为氢化可的松的112.5倍,倍他米松磷酸钠的2.3倍,氟轻松的18.7倍。全身不良反应为氟轻松的3倍,无水钠潴留作用,有一定的促进钠、钾排泄作用。
用途:1、丙酸氯倍他索为人工合成的高效局部外用糖皮质激素类药物。具有较强的抗炎、抗瘙痒和毛细血管收缩作用,其抗炎作用约为氢化可的松的112.5倍,倍他米松磷酸钠的2.3倍,氟轻松的18.7倍。同时具有抑制细胞有丝分裂的作用,能有效地渗透进皮肤角质层。
2、外用适用于慢性湿疹、神经性皮炎、银屑病、掌跖脓疱病、扁平苔藓、盘状红斑狼疮等糖皮质激素,外用治疗有效的瘙痒性及非感染性炎症性皮肤病。
3、具有抗炎、抗过敏、抗增生、免疫抑制作用。
可复方产品:酮康唑。硝酸咪康唑,维A酸 做乳膏和擦剂。
Clobetasol propionate
Synonyms: 17-propionate;cgp9555;clobesol;pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-me;CLOBESTASOL PROPIONATE;CLOBETASOL-17-PROPIONATE;CLOBETASOLE PROPIONATE;CLOBETASOL PROPIONATE
CAS: 25122-46-7
MF: C25H32ClFO5
MW: 466.97
EINECS: 246-634-3
Assay: 99%
Specification: USP32
HS: 2937290090
Appearance: White crystalline powder
Pharmacology toxicology:
This product is rapid, the current clinical application of effective topical corticosteroid medicine effect of a strong. Has the strong capillary contraction, the anti-inflammatory effects of hydrocortisone for 112.5 times, 2.3 times of betamethasone sodium phosphate, 18.7 times fluocinolone. Systemic adverse reactions for 3 times fluocinolone, anhydrous sodium retention effect, have certain promote sodium, potassium excretion.
Usage:
1. clobetasol propionate is a synthetic high topical corticosteroids. Has a strong anti-inflammatory, anti itching and capillary contraction, the anti-inflammatory effects of hydrocortisone is about 112.5 times, 2.3 times of betamethasone sodium phosphate, 18.7 times fluocinolone. At the same time has an inhibitory role in cell mitosis, can effectively penetrate into the skin stratum corneum.
2. external apply to chronic eczema, psoriasis, neurodermatitis, palmoplantar pustulosis, lichen planus, discoid lupus erythematosus, glucocorticoid, topical treatment of pruritic effective and non inflammatory skin disease.
3. has the inhibitory effect of anti-inflammatory, anti allergic, anti proliferation, immune.
Products: compound ketoconazole can. Miconazole nitrate, vitamin A acid cream and liniment.
Packing: 1kg/tin
Price: USD 2592/kg
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