Medscape Scientists have developed a computer model that can predict how drugs will affect the liver, and they have used it to demonstrate that they could have identified the relatively rare risk for hepatotoxicity with the type 2 diabetes drug troglitazone ...
Medscape Pioglitazone, a thiazolidinedione (TZD) for the treatment of type 2 diabetes, has been associated with a number of adverse effects, including fractures and fluid retention, and is contraindicated in patients with class 3 or 4 heart failure. But it has ... and more »
Everyday Health Sulfonylurea stimulates the release of insulin from the pancreas. While the medication does work quickly, it may cause severe low blood sugar, weight gain, nausea, and skin rashes. TZD, or Thiazolidinedione , helps improve the body's sensitivity to ... and more »
FDA.gov The U.S. Food and Drug Administration today approved Trulicity (dulaglutide), a once-weekly subcutaneous injection to improve glycemic control (blood sugar lev...
Diabetes In Control While 24.5% patients on metformin required an add-on oral medication , 37.1% of patients on sulfonylurea, 39.6% of patients on thiazolidinedione , and 36.2% patients on DPP-4 inhibitor required an add-on oral medication . Moreover, 5.1% of patients on ...
HealthDay The researchers found that around 40 percent of people taking a sulfonylurea, a thiazolidinedione , or a dipeptidyl peptidase 4 inhibitor (DPP-4 inhibitor) ad...
청년의사 또한 일부 statin의 대사에 관여하는 Cyt P450 또한 타 fibrate와는 겹치지만, fenofibrate는 Cyt P450에 의해 대사되지 않기 때문에 statin과 fenofibrate 병용 시 서로의 대사에 거의 영향을 미치지 않는다(Expert Opin Drug Saf 2006;5(1):145-56). 따라서 대사 ...
Diabetes News Journal In this study, the authors performed a retrospective analysis and determined how the use of thiazolidinediones (TZDs, a class of drugs used in the treatment of diabetes mellitus type 2) impacts the necessity for re-intervention in diabetic patients ...
