Medscape Scientists have developed a computer model that can predict how drugs will affect the liver, and they have used it to demonstrate that they could have identified the relatively rare risk for hepatotoxicity with the type 2 diabetes drug troglitazone ...
American Pharmacists Association, pharmacist.com ... as dulaglutide include the low risk of hypoglycemia, especially when administered with metformin or a thiazolidinedione ; the weight-loss effects of these agents; and potential adherence benefits associated with drugs that only require once-weekly ...
Daytona Beach News-Journal I exercise, stay slim and think I am reasonably careful about my diet. Subtract the dark-chocolate habit and minus the Cheetos cravings, I make fairly good choices. So I was shocked to learn that my fasting blood sugars were bordering on high and my ... and more »
Everyday Health Sulfonylurea stimulates the release of insulin from the pancreas. While the medication does work quickly, it may cause severe low blood sugar, weight gain, nausea, and skin rashes. TZD, or Thiazolidinedione , helps improve the body's sensitivity to ... and more »
FDA.gov The U.S. Food and Drug Administration today approved Trulicity (dulaglutide), a once-weekly subcutaneous injection to improve glycemic control (blood sugar lev...
HealthDay The researchers found that around 40 percent of people taking a sulfonylurea, a thiazolidinedione , or a dipeptidyl peptidase 4 inhibitor (DPP-4 inhibitor) ad...
Diabetes In Control While 24.5% patients on metformin required an add-on oral medication , 37.1% of patients on sulfonylurea, 39.6% of patients on thiazolidinedione , and 36.2% patients on DPP-4 inhibitor required an add-on oral medication . Moreover, 5.1% of patients on ...
Medscape Pioglitazone, a thiazolidinedione (TZD) for the treatment of type 2 diabetes, has been associated with a number of adverse effects, including fractures and fluid retention, and is contraindicated in patients with class 3 or 4 heart failure. But it has ... and more »
Diabetes In Control The medication can be used as monotherapy or in combination with other agents for optimal glycemic control in type 2 diabetes patients. The use of combination therapy utilizes medications that offer different mechanisms of action for improved glycemic ...