Seeking Alpha This trial has now concluded and did not demonstrate an improvement in progression-free survival in the combination group when compared to docetaxel alone, the primary endpoint of the trial. We're continuing to analyze these data, which will be ... and more »
Sacramento Bee The first Phase 1/2 trial is evaluating PX-866 in combination with the chemotherapeutic agent docetaxel (Taxotere®). The Phase 2 portion of the trial is an open-label, randomized evaluation of the antitumor activity and safety of PX-866 administered at ... and more »
Seeking Alpha In April, we calculated that about 51% of the patients who received at least one cycle of labeled clivatuzumab with oral gemcitabine were alive. Although there have been many drug failures in pancreatic cancer indication, we believe that our technology ... and more »
PipelineReview.com (press release) Suppression of the PGP pump allows certain clinically important compounds (such as Paclitaxel and Irinotecan , among others) which would normally be effluxed back into the gastrointestinal tract and excreted, to enter the bloodstream and be bioavailable ... and more »
Wall Street Journal In addition, Pexa-Vec is being evaluated in a Phase 1-2 clinical trial in patients with treatment-refractory colorectal cancer as monotherapy and in combination with irinotecan , and in a Phase 2a clinical trial in treatment-refractory kidney cancer ...
EON: Enhanced Online News (press release) “In colorectal cancer, we plan to present final data from our Phase 2 trial of tivantinib in combination with irinotecan and cetuximab at the ASCO Annual Meeting in June,” said Mr. Pucci. “The presentation will include mature overall survival data from ...
pharmabiz.com Vectibix was approved in the US in September 2006 as a single agent for the treatment of metastatic colorectal carcinoma with disease progression on or following fluoropyrimidine, oxaliplatin and irinotecan chemotherapy regimens. Approval is based on ...
Canada NewsWire (press release) The authors concluded that the combination of REOLYSIN and FOLFIRI was safe and well tolerated and resulted in disease control in the majority of evaluable patients, including patients that had previously progressed on Irinotecan ;. Clinical Trial ... and more »
Oncology Nurse Advisor Vectibix, a human anti-epidermal growth factor receptor (EGFR) antibody is approved for the treatment of metastatic colorectal carcinoma with disease progression on or following fluoropyrimidine-, oxaliplatin-, and irinotecan -containing chemotherapy ... and more »
PipelineReview.com (press release) Suppression of the PGP pump allows certain clinically important compounds (such as Paclitaxel and Irinotecan , among others) which would normally be effluxed back into the gastrointestinal tract and excreted, to enter the bloodstream and be bioavailable ...
