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已读[250] 发布: 2013/07/03 19:50:37
OncLive Last October, the agent was approved as a first-line treatment for locally advanced or metastatic non-small cell lung cancer (NSCLC); it is now undergoing a priority review as a first-line treatment in combination with gemcitabine for patients with ...
已读[261] 发布: 2013/07/03 19:50:33
Seeking Alpha PCI-24781 in particular is scheduled to complete a Phase II safety study in combination with gemcitabine in pancreatic cancer patients this month. Data is expected in Q3 2013. The company is also exploring the efficacy of BTK inhibition in autoimmune  ... and more »
已读[416] 发布: 2013/07/03 19:50:29
Medscape Six months later, gemcitabine was introduced, followed by carboplatin and pemetrexed. In early 2012, frontal metastasis was treated with stereotaxic surgery and radiotherapy, and a TORC1/TORC2 inhibitor was initiated soon afterward. The patient did not  ...
已读[265] 发布: 2013/07/03 19:50:10
PipelineReview.com (press release) A total of 58 patients were randomized to receive either 90Y-labeled-clivatuzumab once-a-week for 3 weeks at 6.5 mCi/m2 with gemcitabine 200 mg/m2 given weekly x 4 weeks (Arm A) or 90Y-labeled-clivatuzumab alone (Arm B). This treatment cycle was  ... and more »
已读[251] 发布: 2013/06/22 13:29:55
This is Money Silence Therapeutics (up 1.2 per cent today at 170p) has successfully negotiated the initial safety assessment of its cancer drug Atu027. It is being used in combination with gemcitabine , the most common chemotherapy, to treat pancreatic cancer, the ...
已读[261] 发布: 2013/06/22 13:29:38
Healio CHICAGO — The addition of nanoparticle albumin-bound paclitaxel to gemcitabine increased response and extended OS compared with gemcitabine alone in patients with metastatic pancreatic cancer, according to results of an international randomized,  ...
已读[308] 发布: 2013/06/18 22:10:34
(R1)可分别用作铂类药物与吉西他滨(G)的预测标记物。在一项II期临床试验中,E1和R1 mRNA表达水平被用于确定治疗策略,最终患者缓解率为44%,PFS为6.6个月,OS为13.3个月。 方法:本研究合格入选人群为,未经过化疗治疗、PS0-1、病情可测的晚期NSCLC患者,...
已读[310] 发布: 2013/06/18 22:10:26
本研究的目的在于评估在早期三阴性和BRCA1/2突变相关的乳腺癌患者中,应用Iniparib联合吉西他滨和卡铂的有效性、安全性以及评价患者对治疗的反应。 本研究为单队列、II期临床研究(NCT00813956),...
已读[252] 发布: 2013/06/18 22:10:22
pharmabiz.com The SmPC is available at www.pixuvri.eu. CTI is currently accruing patients into a Phase 3 trial comparing PIXUVRI and rituximab with gemcitabine and rituximab in the setting of aggressive B-cell NHL. PIXUVRI does not have marketing approval in the ... and more »
已读[260] 发布: 2013/06/18 22:10:18
The Biological SCENE During that prime-time slot, the study's investigator, Texas Oncology breast cancer expert Joyce A. O'Shaughnessy, reported that adding the compound to a chemotherapy regimen of gemcitabine and carboplatin prolonged survival in women with  ...
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