Seeking Alpha And that has been replicated in the pancreatic cancer model using it with gemcitabine , also known to induce TNF. You see good synergy when you combine 427 with a TNF-inducing agent. So Phase I trial was completed by Genentech, 42 patients were ... and more »
Hamilton Spectator "There is no evidence of any malicious or deliberate drug-sparing dilution in preparing the bags of cyclophosphamide or gemcitabine by (Marchese Hos...
Proactive Investors UK In April, Silence started dosing of pancreatic cancer patients with the chemotherapy agent gemcitabine in combination with its lead product Atu027 and will follow this up with other chemotherapy agents in a variety of tumour types. If successful ... and more »
GenomeWeb In light of those data, Silence has recently begun dosing patients in the first portion of a phase Ib/IIa study that will examine Atu027 in combination with th...
Healio Maintenance therapy with paclitaxel and gemcitabine improved PFS and OS in women with metastatic breast cancer who initially exhibited disease control after first-line treatment with six cycles of the same combination, according to results of a phase 3 ...
Trefis The company's lead drug candidate, NeuVax (nelipepimut-S or E75), a cancer vaccine, is already in a phase 3 trial. It does ... EH: The company did not separate cohorts between the HER2-overexpressing and HER2 low- or intermediate -expressing patients.
Financial Times This was to advance his work by combining the cancer treatment gemcitabine with squalene, a lipid or insoluble compound, that stops tumours for pancreatic cancer growing. He is examining the combination of nanoparticles and magnetic nano-crystals ...
Toronto Star “There is no evidence of any malicious or deliberate drug-sparing dilution in preparing the bags of cyclophosphamide or gemcitabine by (Marchese Hospital ...
Business Wire (press release) “Results of a randomized phase III trial (MPACT) of weekly nab-paclitaxel plus gemcitabine versus gemcitabine alone for patients with metastatic adenocarcinoma of the pancreas with PET and CA19-9 correlates.” Daniel Von Hoff, M.D., F.A.C.P., chief ... and more »
