Medscape In the trials, the most common adverse events with liraglutide 3.0 mg vs placebo were nausea (39% vs 14%), diarrhea (21% vs 10%), vomiting (16% vs 4%), and hypoglycemia when used in combination with sulfonylureas despite a halving of the sulfonylurea ... and more »
Healio Ulrik M. Mogensen, MD, of the department of cardiology at University Hospital Rigshospitalet in Denmark, and colleagues evaluated 11,081 patients receiving sulfonylurea with insulin and 16,910 patients receiving metformin with insulin to determine the ... and more »
Medical Xpress The Federal Joint Committee (G-BA) specified different appropriate comparator therapies for the subindications, resulting in a total of five comparisons: empagliflozin as monotherapy versus a sulfonylurea (A), in combination with metformin versus ... and more »
News-Medical.net The Federal Joint Committee (G-BA) specified different appropriate comparator therapies for the subindications, resulting in a total of five comparisons...
ADVANCE for Physician Assistants In patients receiving canagliflozin in combination with insulin/ sulfonylurea , glucose monitoring may be appropriate and adjustments in insulin/ sulfonylurea dose may be needed to reduce the risk of hypoglycemia. 2 Canagliflozin was associated with early ...
Insurance News Net A sulfonylurea can be a useful, rapid-acting alternative to insulin if a patient with T2DM is not already taking one. In preparation for surgery, a sulfonylurea can improve HbA1c in patients where its long-term use was being avoided to minimise weight ... and more »
Diabetes In Control This study examined the efficacy of saxagliptin when used in combination therapy with metformin, a sulfonylurea , a thiazolidinedione or insulin. It also examined saxagliptin's use in triple therapy with metformin and a sulfonylurea . Separate randomized ...
The Pharmaceutical Journal Joanna is a freelance medical writer with a BSc (Hons) in Medical Science & Pharmacology and 15 years' experience working in the field of medical communications. Journalistic work includes clinical research summaries, interviews, feature articles and ...
AJMC.com Managed Markets Network Study Design: Patients with T2DM who were treated with saxagliptin (N = 13,929), sulfonylurea (N = 117,756), or sitagliptin (N = 36,813) in 2010 or later were identified in a database of commercially insured beneficiaries. Patients were required to ...
AJMC.com Managed Markets Network One trial evaluated patients on metformin at baseline with add-on canagliflozin 100 mg, canagliflozin 300 mg, or sitagliptin 100 mg; the other trial evaluated patients on metformin and a sulfonylurea at baseline with add-on canagliflozin 300 mg or ... and more »
