Monthly Prescribing Reference The primary outcome was to determine the risk for the association between sulfonylurea use and incident cardiovascular disease. During the time period of the study, 191 cases of CHD and 148 cases of stroke were identified. The risk of CHD was greatest ...
Medical Research News and Interviews_ MedicalResearch.com Dr. Hu: in this study among approximately 5000 patients with type 2 diabetes followed for up to 10 years, longer duration of sulfonylurea therapy was associated with a higher risk of coronary heart disease. The continuous sulfonylurea therapy for 10 ...
MarketWatch When JANUVIAwas used in combination with a sulfonylurea or insulin, medications known to cause hypoglycemia, the incidence of hypoglycemia was increased over that of placebo. Therefore, a lower dose of sulfonylurea or insulin may be required to ... and more »
Healio In the study, researchers evaluated 4,902 women with type 2 diabetes who responded to a supplemental questionnaire in 2000 and 2005 as part of the Nurses' Health Study cohort to determine the association between sulfonylurea use and the risk of ... and more »
MedPage Today SGLT2s were added on to metformin instead of sulfonylurea in three trials, showing slightly better HbA1c control (-0.12%), greater weight loss (4.81 kg or 10.6 lbs), greater reduction in blood pressure (5.12 mm Hg), and less hypoglycemia. Five trials ...
Medscape VIENNA — Two-year results of a head-to-head trial comparing the sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin (Jardiance, Boehringer Ingelheim) with the sulfonylurea glimepiride as second-line therapy after metformin in patients with ...
Diabetes In Control However, according to Dr. Yanping Li from the department of Nutrition at Harvard School of Public Health in Boston, Massachusetts, evidence for the association between sulfonylurea use and risk of cardiovascular disease among diabetic patients is ...
MedPage Today It may be used with other drugs including metformin, sulfonylurea agents, thiazolidinediones, and/or prandial insulin, the agency said, but should not be considered for first-line drug therapy. Some in the field had looked to once-weekly treatments as ...
Pharmacy Times ... once daily significantly reduced glycated hemoglobin (A1C) in T2DM patients who had not achieved adequate control with diet and exercise,8 metformin,9 sulfonylurea ,10 combination metformin and sulfonylurea ,11 combination metformin and pioglitazone ...
Forbes The drug can be given as monotherapy or in combination with other diabetes drugs including metformin, sulfonylurea , thiazolidinediones, and prandial insulin. It...
