7thSpace Interactive (press release) Conclusions: We estimate that antibiotic resistance in pneumococcal pneumonia leads to substantial healthcare utilization and cost, with more than one-third driven by macrolide resistance in children. With 5% of total pneumococcal costs directly ...
MedPage Today Another study has disputed the relationship between the use of azithromycin, a macrolide antibiotic, and the risk of cardiovascular death. In a cohort of more than a quarter million young patients with chlamydia, gonorrhea, or both, there were no ...
Medscape Tacrolimus, a macrolide derived from the bacterium Streptomyces tsukubaensis, is a potent immunomodulator capable of decreasing the production of inflammatory mediators by T lymphocytes through the inhibition of calcineurin, an intracytoplasmic protein ...
Infection Control Today Physicians prescribed extended macrolides (a type of antibiotics) at 36 percent of acute bronchitis visits, and extended macrolide prescribing ...
Medscape Prescriptions for 1 type of antibiotic, macrolide , spiked from 25% of visits in 1996 to 1998 to 41% in 2008 to 2010 (P = .01). Other antibiotics were prescribed at 35% (95% CI, 30% - 39%) of visits. For 15 years, the CDC has urged providers to stop ...
Seeking Alpha Cempra is developing a new macrolide antibiotic by the name of solithromycin. No new macrolide antibiotic has been marketed since Ketek (telithromycin) in 2004, which has had limited use due to rare but very serious liver toxicity. As mentioned in the ... and more »
Wall Street Journal Omeclamox-Pak is contraindicated in patients with a history of hypersensitivity to omeprazole, any macrolide antibiotic or penicillin. The safety and effectiveness of Omeclamox-Pak in the pediatric population has not yet been established. Omeclamox-Pak ... and more »
Chemistry World If you've read a Fürstner macrolide synthesis from the last decade or so, you might expect it to feature the group's signature reaction: ring-closing alkyne metathesis. This highly chemoselective reaction is almost always performed on internal alkynes, ...