Medscape Tacrolimus, a macrolide derived from the bacterium Streptomyces tsukubaensis, is a potent immunomodulator capable of decreasing the production of inflammatory mediators by T lymphocytes through the inhibition of calcineurin, an intracytoplasmic protein ...
Medscape Prescriptions for 1 type of antibiotic, macrolide , spiked from 25% of visits in 1996 to 1998 to 41% in 2008 to 2010 (P = .01). Other antibiotics were prescribed at 35% (95% CI, 30% - 39%) of visits. For 15 years, the CDC has urged providers to stop ...
Grand Haven Tribune During the entire study period, 36 percent of those patients got a prescription for an extended macrolide , a group that includes such workhorses as azithromycin and erythromycin. Another 35 percent got an Rx for a broad-spectrum antibiotic, including ...
AAP News (subscription) Infants treated with macrolide antibiotics were at a significantly increased risk of developing infantile hypertrophic pyloric stenosis (IHPS), according to a study of 999,378 babies born in Denmark between 1996-2011. Macrolides, including erythromycin ...
Medscape Macrolide treatment of Mycoplasma pneumoniae may or may not benefit children with community-acquired lower respiratory tract infection (CA-LRTI), according to an article published in the June issue of Pediatrics. Eric Biondi, MD, from the Department of ...
Seeking Alpha At least 30% of pneumococci in the U.S. are now resistant to azithromycin, the best-selling macrolide , and resistance in Asia has been reported to be much higher. To address the "superbug" crisis and encourage development of new antibiotics, several ... and more »
Wall Street Journal Omeclamox-Pak is contraindicated in patients with a history of hypersensitivity to omeprazole, any macrolide antibiotic or penicillin. The safety and effectiveness of Omeclamox-Pak in the pediatric population has not yet been established. Omeclamox-Pak ... and more »
Chemistry World If you've read a Fürstner macrolide synthesis from the last decade or so, you might expect it to feature the group's signature reaction: ring-closing alkyne metathesis. This highly chemoselective reaction is almost always performed on internal alkynes, ...
NASDAQ Prabhavathi Fernandes, Ph.D., president and chief executive officer of Cempra said, "We continue to collect exciting data on the emerging profile of solithromycin, our fourth-generation macrolide . The data presented at this year's ECCMID are excellent ... and more »
Seeking Alpha The significant decrease in the income from operations were mainly due to the fixed costs in operation of manufacturing and an increase of operating costs ...
