OncLive Clinicians should offer preventive therapy for fractures and skeletal-related events (SREs). For patients with bony metastases, treating physicians may offer denosumab or zoledronic acid for prevention of SREs. “Although our primary objective was ...
GlobeNewswire (press release) The increase was driven by $21.3 million in revenue from the launch of 32 new codes or presentations of 16 new products since March 31, 2012, including Zoledronic acid at market formation. Gross profit for the first quarter of 2013 was $18.5 million ... and more »
The Myeloma Beacon ... Findings from a retrospective study show that the bisphosphonates Boniva (ibandronate), Aredia (pamidronate), and Zometa ( zoledronic acid ) may not significantly decrease kidney function in multiple myeloma patients undergoing stem cell transplantation.
Healio It has been established in previous studies that zoledronic acid improves bone density and reduces risk for fracture. However, new data suggests it may also sig...
Journal of Clinical Endocrinology and Metabolism Main Outcomes Measures: At baseline and then at 2, 7, 30, and 360 days after zoledronic acid or placebo administration, serum levels of sclerostin, bone-specific alkaline phosphatase (BSAP), as a bone formation marker, and serum C-telopeptide of type 1 ...
Medscape According to Catalano, "since inhibition of sclerostin...may promote [bone formation], new studies testing the…additional benefits to bone mass resulting from combined therapy between bisphosphonates…and [drugs that inhibit ] sclerostin…are needed ...
