GlobeNewswire (press release) Resistance to carbapenems has been highlighted as a particular concern because carbapenems are one of the last lines of defense against antibiotic-resistant gram-negative infections. Most CRE express enzymes called carbapenemases, which break down ... 更多 »
VRT Nieuws Ze wilden vooral de toenemende resistentie onderzoeken tegen carbapenems , de enige klasse van beta-lactam-antibiotica waarvoor vele bacteriën en superbacteriën als E.coli nog gevoelig zijn. Resistentie tegen carbapenems maakt sommige infecties ... 更多 »
University of Bristol A carbapenem molecule, a last resort antibiotic, enters the carbapenemase enzyme (blue arrow), where the crucial beta-lactam structure gets broken down. The ineffective molecule then leaves (orange arrow). Press release issued: 17 October 2014.
Scientific Computing A carbapenem molecule, a last resort antibiotic, enters the carbapenemase enzyme (blue arrow Scientists have used computer simulations to show how bacteria are able to destroy antibiotics — a breakthrough that will help develop drugs which can ...
科学时报 (博客) They designed their RNA guide strands to target genes for antibiotic resistance, including the enzyme NDM-1, which allows bacteria to resist a broad range of beta-lactam antibiotics, including ... 更多 »
The Guardian We began by targeting genes that make beta-lactamase enzymes, which allow bacteria to destroy an important class of antibiotics – including penicillin and carbapenems – before they can do their work. This is an issue of global concern because drugs ...
Monthly Prescribing Reference PHILADELPHIA, PA—Patients with carbapenem -resistant Klebsiella pneumoniae who are hospitalized and treated with a tigecycline-based regimen are at high risk of readmission with recurrent disease, contributing to its spread in healthcare systems ...
DigitalJournal.com The scientists were most interested in the growing resistance of bacteria to carbapenems . This type of antibiotic ism often referred to as the 'last resort' antibiotic. The concern is that if increasing types of bacteria become resistant to carbapenems ...
R & D Magazine A carbapenem molecule, a last resort antibiotic, enters the carbapenemase enzyme (blue arrow Scientists have used computer simulations to show how bacte...
