卡托普利(疏甲丙脯酸、甲疏丙脯酸、开搏通) Captopril (Capote, Lopirin, Tensiomin) 化学名称:1-(3-巯基-2-D-甲基丙酰基)-L-脯氨酸 英文化学名称: 1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline;D-2-Methyl-3-mercaptopropanoyl-L-proline; 分子式为:C9H15NO3S 分子量:217.28 CAS号:62571-86-2 熔点:103-108°C 比旋光度:-129.5° (c=1, EtOH) 临床应用:用于治疗各种类型的高血压症,尤对其他降压药治疗无效的顽固性高血压,与利尿剂合用可增强疗效,对血浆肾素活性高者疗效较好。也用于急、慢性充血性心衰,与强心剂或利尿剂合用效果更佳。 Captopril is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure. Captopril was the first ACE inhibitor developed and was considered a breakthrough both because of its novel mechanism of action and also because of the revolutionary development process. Captopril is commonly marketed by Bristol-Myers Squibb under the trade name Capoten.