JEMS.com Some common classes of drugs known to prolong the QT interval are antiarrhythmic drugs, macrolide antibiotics, certain psychotropic medications and gastric motility agents. Hypokalemia and hypomagnesemia may also predispose a patient to TDP.
Equities.com Cempra Inc. (CEMP) , with a valuation approaching $1 billion ($1B), is not a small cap, but "has a promising macrolide antibiotic, solithromycin, which just read out Phase 3. It's for community-acquired pneumonia and other indications." He also likes ...
HCPLive Community-acquired pneumonia presents a number of dilemmas. Patients may be elderly or frail and it's sometimes difficult to identify the infectious organism initially. There is considerable debate about the selection of an appropriate antibiotic or ...
Seeking Alpha Cempra's (NASDAQ:CEMP) Solithromycin seems to be the answer to such macrolide resistant pathogens and that too with minimal side effects. The drug is a ketolide which makes it more potent than prevalent macrolide treatments but does not have the side ... and more »
SYS-CON Media (press release) Based on the nature of JCM's antibiotic business specializing on API manufacturing and sales, TPI's Jiangchuan macrolide facility (JCM), a wholly owned subsidiary of Chengdu Tianyin, currently valued at $18 million, along with other assets under TPI ... and more »
7thSpace Interactive (press release) In addition to antimicrobial effects, macrolide antibiotics are known to possess immunomodulatory properties.We aimed to evaluate inflammatory cytokine profiles ? both locally (bronchoalveolar lavage) and systemically (blood) ? in community-acquired ...
Healio “Widespread use of 1g azithromycin for M. genitalium has been associated with emergence of macrolide resistance and declining cure rates in some settings,” researchers wrote in Clinical Infectious Diseases. “Moxifloxacin has been shown to be effective ...
